Isomura was born in Tokyo, Japan in 1992 and graduated from the Department of Painting of Tokyo University of the Arts, majoring in oil painting in 2016. Although his works are characterized as folk (ethnically) and vernacular (indigenous), but on the other hand, he creates with the consciousness of transnational perspectives. This is why Isomura's works are so difficult to understand. His works are established based upon transcendence in various constraints of gender, national borders, race, and intentionally considering the problems of others as his own. The actuality of self and others overlaps with the reality of society respectively. In recent years, Isomura has been focusing on LGBTQ, queer, immigrants and refugees’ issues, religious perspectives and so on that have been taken as the themes of his works.
In 2019, supported by grants from the Asian Cultural Council fellowship, Isomura was involved in short term activities in New York. He received the Forbes JAPAN “30 UNDER 30 JAPAN 2019” Art prize, Asian Art Biennial 2021 (National Taiwan Museum of Fine Arts in 2020), and “CITY is NATURE” (Sezon Museum of Modern Art, Nagano, Japan, 2021) and so on.