Djordjadze was born in Tbilisi, Georgia in 1971. She studied at the Tbilisi State Academy of Art in 1988. However, due to the unstable political situation caused by the civil war, she left the country and transferred to the Gerrit Rietveld Academie in Amsterdam from 1993 to 1994. She then studied at the Kunstakademie Düsseldorf in 1994. Djordjadze returned and continued her studies at the Tbilisi State Academy of Art after the political situation in Georgia became stable in 1995 and completed her studies at Kunstakademie Düsseldorf in 2001. Since then, she has lived and is based in Berlin. Djordjadze is known for her wide range of expressions through sculpture, installation, and painting. She is particularly remarkable for her on-site, expansive installations developed through conceptual and architectural arrangement. Her creative practice of transforming and rearranging industrial materials and objects coming from everyday life perhaps is influenced by minimalism and modernist architecture. She has received high acclaim at international exhibitions including the Berlin Biennale in 2008, the dOCUMENTA (13) (Kassel, 2012), and in the Venice Biennale in 2015. She has also had solo exhibitions at MoMA PS1 (New York, 2016), Portikus (Frankfurt, 2018), Musée d’art moderne et contemporain, Saint-Étienne Métropole (MAMC) in 2022. Her artworks are included in the collections of major contemporary art museums in Europe and in the United States, such as MoMA (NY), Migros Museum (Zurich), Musée d’art moderne et contemporain, Saint-Étienne Métropole (MAMC), Neues Museum (Berlin), The Lenbachhaus (Munich), and the Berlinische Galerie (Berlin) etc.